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Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research
book

Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research

by Chul Ahn, Moonseoung Heo, Song Zhang
December 2014
Intermediate to advanced content levelIntermediate to advanced
260 pages
8h 51m
English
Chapman and Hall/CRC
Content preview from Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research
Sample Size Determination for Clustered Outcomes 53
TABLE 2.3
Stepped wedge design, where C represents control and I represents interven-
tion
Cluster Number Intervention
1 C I I I I I I
2 C C I I I I I
3 C C C I I I I
4 C C C C I I I
5 C C C C C I I
6 C C C C C C I
clusters cross over in one direction only, for example from control to interven-
tion. Table 2.3 shows the intervention sequence of the stepped wedge design.
Woertman et al. [61] derived the design effect (also called sample size
correction factor) from the formulas provided by Hussey and Hughes [60]
assuming that cluster size (m) is equal across all clusters. The design effect
can be used to estimate ...
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Publisher Resources

ISBN: 9781466556270