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Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research
book

Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research

by Chul Ahn, Moonseoung Heo, Song Zhang
December 2014
Intermediate to advanced content levelIntermediate to advanced
260 pages
8h 51m
English
Chapman and Hall/CRC
Content preview from Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research
66 Sample Size Calculations for Clustered and Longitudinal Outcomes
The sample size formulas presented here are simplified versions of Overall
and Doyle [10], which provided equations for calculating z
1β
to test the
“equal change hypothesis” using simple difference scores or ordinary least
squares (OLS) regression slopes or generalized least squares (GLS) regression
slopes as dependent variables. Let ∆
be the effect size, which is the clinically
or scientifically meaningful difference between treatment means expressed in
standard deviation units. The general power equation for testing “equal change
hypothesis” between two treatment groups is of the form ...
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Publisher Resources

ISBN: 9781466556270