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Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research
book

Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research

by Chul Ahn, Moonseoung Heo, Song Zhang
December 2014
Intermediate to advanced content levelIntermediate to advanced
260 pages
8h 51m
English
Chapman and Hall/CRC
Content preview from Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research
Sample Size Determination for Repeated Measurement Outcomes 71
the inverse of the within–subject correlation matrix of the repeated measure-
ments.
Chapter 4 includes additional discussion of sample size approaches for
the comparisons of rates of change under various correlation structures, and
missing data patterns. Chapter 5 also includes additional discussion of sample
size approaches for the comparisons of rates of change in two–level longitudinal
designs under the assumption of a fixed slope and a random slope.
3.3.4 Difference in Rate of Change across Time with Baseline
Covariate
The linear trend scores are not generally independent of baseline
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Publisher Resources

ISBN: 9781466556270