Chapter 15. Nonlinear Mixed Models

15.1

Introduction

568

15.2

Background on PROC NLMIXED

569

15.3

Example: Logistic Growth Curve Model

571

 

15.3.1

PROC NLMIXED Analysis

571

 

15.3.2

%NLINMIX Macro Analysis—Method 1

575

 

15.3.3

%NLINMIX Macro Analysis—Method 2

581

 

15.3.4

%NLINMIX Macro Analysis—Method 3, With and Without Variance Weighting

581

 

15.3.5

Choosing the Exponent for the Weight Matrix That Leads to the Best Fit

586

 

15.3.6

Comparing the Logistic Model Fitting Methods

586

15.4

Example: Nested Nonlinear Random Effects Models

587

15.5

Example: Zero-Inflated Poisson and Hurdle Poisson Models

589

15.6

Example: Joint Survival and Longitudinal Model

595

15.7

Example: One-Compartment Pharmacokinetic Model

607

15.8

Comparison of PROC NLMIXED and the %NLINMIX Macro

623

15.9

Three General ...

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