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Second Harmonic Generation Imaging
book

Second Harmonic Generation Imaging

by Francesco S. Pavone, Paul J. Campagnola
April 2016
Intermediate to advanced content levelIntermediate to advanced
476 pages
21h 10m
English
CRC Press
Content preview from Second Harmonic Generation Imaging
SHG Imaging of Collagen and Application to Fibrosis Quantization 359
tissues. Indeed, inammation has been shown to correspond to an increase of the endogenous uo-
rescence of the tissue. It is presumably due to a strong metabolic activity of the cells involved in the
inammatory response. An example is displayed in Figure 15.2a: we observe many circular structures
that exhibit a strong 2PEF signal and are less present in control lungs. ese round cells have been
shown to correspond to macrophages using immunochemical labeling (Pena etal. 2007). Combined
SHG/2PEF microscopy therefore enables the discrimination of two major pathological processes, ...
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Publisher Resources

ISBN: 9781439849156