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Separation Process Engineering: Includes Mass Transfer Analysis, Third Edition by Phillip C. Wankat

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18.2 Solute Movement Analysis for Linear Systems: Basics and Applications to Chromatography

Packed columns similar to Figure 18-1 are the most common contacting devices used for adsorption and chromatography. Although there are exceptions, they are usually operated vertically with the flow parallel to the axis of column. Adsorption, chromatography, and ion exchange in packed columns are inherently unsteady state or batch type processes. Since the sorbent is stationary, it will saturate at the feed concentration if feed enters the column continuously. Thus, there must also be a regeneration step that removes most of the sorbate from the packing. The commonly used regeneration methods are to use an inert purge stream, change the temperature, change ...

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