
160
ssf for foods and beverages
improved following the fermentation. ACE- inhibitory activities of
48 hrs with primary fermented douchi qu did not change dramati-
cally after preincubation with ACE, but increased greatly after pre-
incubation with gastrointestinal proteases. e results suggest they
were pro- drug- type or a mixture of pro- drug- type and inhibitor- type
inhibitors (Figure6.3). e ACE inhibitors in 48-hour fermented
douchi qu were fractionated into four major peaks by gel filtration
chromatography on Sephadex G-25. Peak 2, which had the highest
activity, had only one peptide, composed of phenylalanine, isoleucine,
and ...