4.3 Results

4.3.1 Community Maps

The communities retrieved for each subnetwork are listed in Table 4.1, and Figure 4.2 describes the comparative algorithmic performance through the maximal values achieved by Q for each PIN. Then, Figures 4.34.6 represent instead examples of community maps computed for the relevant subnetworks, that is, cPIN, cePIN, cePIN-1, and cePIN-2, respectively. A characterization for the module maps is obtained by the cell cycle phases, that is, the S (synthesis, DNA replication) and M (mitosis, chromosome separation) phases together with the remaining G1 and G2 interphases. For both cePIN-1 and cePIN the corresponding KEGG pathways have also been reported as supplementary data (SD).

Table 4.1 Detected Communities (Relatively Small Ones)

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Table 4.2 Number of MCODE-Detected k-Cores at k Ranging Between Minimum of 2 and Maximum of 13 Across PIN.

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Figure 4.3 Community maps: (a) cPIN and (b) cePIN-1. The thick arrows point out the indicated hubs.

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Figure 4.4 Community maps: (a) cePIN and (b) cePIN-2.

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Figure 4.5 Best k-core cPIN.

Figure 4.6 Best k-core intersection ...

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