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Synthetic Gene Network
book

Synthetic Gene Network

by Bor-Sen Chen, Yu-Chao Wang
May 2014
Intermediate to advanced content levelIntermediate to advanced
216 pages
6h 47m
English
CRC Press
Content preview from Synthetic Gene Network
3
Robust Synthetic Biology
Designs based on System
Dynamic Models
3.1 Robust Synthetic Biology Design to Satisfy Design
Specifications
Based on the stochastic gene network in (2.15) and the design specifi cations
(2.16)–(2.19) in previous chapter, we now can introduce the robust synthetic
biology design to satisfy design specifi cations. Our design goal is to choose
some kinetic parameters and decay rates in the stoichiometric matrix N from
the biologically feasible parameter range
[
12
,NN
[
]
such that the desired
steady state x
d
in (2.18) can be achieved, the stochastic parameter variations
()
1
m
ii i
i
Mg x dW
=
can be robustly tolerated (stabilized), ...
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Publisher Resources

ISBN: 9781466592698