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Synthetic Gene Network
book

Synthetic Gene Network

by Bor-Sen Chen, Yu-Chao Wang
May 2014
Intermediate to advanced content levelIntermediate to advanced
216 pages
6h 47m
English
CRC Press
Content preview from Synthetic Gene Network
6.1.2 In silico design examples
In this section, two in silico design examples are given to illustrate the
design procedure of the proposed library-based search method. First of
all, synthetic biologists need to engineer a genetic circuit topology, and
then a dynamic model could be constructed. Finally, the proposed library-
based search method is used to obtain the most adequate promoter set
*** *
12
{, , , }
n
ccc c=
.
6.1.2.1 Design of synthetic transcription cascade
Consider the dynamic system (6.3) of the synthetic transcriptional cascade
shown in Figure 6.1. The design specifi cations are provided and listed as
follows:
i) The desired reference trajectory to be tracked is
()
6
7
10 , 40, 80
2 10 , 40 80
r
tt
yt
t
≤>
=
×<≤
(6.8)
i.e., the refer ...
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Publisher Resources

ISBN: 9781466592698