
7
Robust Design of Synthetic
Biological Filter and
Transistor based on
Promoter-RBS Libraries
In this chapter, two design examples, namely, robust design of synthetic
biological fi lter and transistor, are given to demonstrate the systematic
design methodology of synthetic gene networks based on promoter-RBS
libraries constructed in Chapter 5.
7.1 Systematic Design Methodology for Synthetic Biological
Filter
7.1.1 A cascade gene circuit topology for biological filter design
After promoter-RBS libraries are built from the promoter-RBS strengths,
a set of biological components from the promoter-RBS libraries in Table
5.4−5.7 and the corresponding r ...