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The Alzheimer Conundrum by Margaret Lock

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Chapter 1

Making And Remaking Alzheimer Disease

I … now see my reluctance to apply the term Alzheimer’s to my father as a way of protecting the specificity of Earl Franzen from the generality of a named condition. Conditions have symptoms; symptoms point to the organic basis of everything we are. They point to the brain as meat. And, where I ought to recognize that, yes, the brain is meat, I seem instead to maintain a blind spot across which I then interpolate stories that emphasize the more soul-like aspects of the self.

—Jonathan Franzen, “My Father’s Brain”1

In January 2011 I attended a lecture delivered in an engaging manner in a Montréal hospital about pathbreaking basic science research in connection with amyloid plaques and neurofibrillary ...

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