Chapter 14

Moderate Red Wine Consumption in Cardiovascular Disease

Ethanol Versus Polyphenols

Marcello Iriti, PhD1; Elena M. Varoni, DD, PhD1,2,3    1 Milan State University, Milan, Italy2 McGill University, Montreal, QC, Canada3 University of Eastern Piedmont ‘A. Avogadro’, Novara, Italy


For decades it has been suggested that regular, moderate consumption of red wine, a major component of the Mediterranean diet, at main meals may contribute to explaining the healthy properties attributed to this traditional dietary style. Although preclinical in vitro and in vivo data have shown a significant cardioprotective activity of grape phytochemicals, mostly polyphenols, evidence in humans ...

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