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Biodegradable and bioactive polymer/inorganic phase nanocomposites for bone tissue engineering (BTE)

V. Miguez-Pacheco,    University of Erlangen-Nuremberg, Germany

S.K. Misra,    University of Birmingham, UK

A.R. Boccaccini,    University of Erlangen-Nuremberg, Germany

Abstract:

Scaffolds for bone tissue engineering (BTE) must be mechanically competent and chemically compatible with bone tissue to repair defects. Polymeric materials exhibit suitable mechanical and processing abilities but lack the bioactivity of inorganic ceramics. Composites of these materials are being developed to combine and improve their properties. It has become evident that cells respond to the topography of the surrounding extracellular matrix, specifically to nano-sized ...

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