Q.Z. Chen, Monash University, Australia
S.E. Harding, Imperial College London, UK
R. Rai and A.R. Boccaccini, University of Erlangen-Nuremberg, Germany
In the pursuit of engineering a functional myocardium, studies integrating highly innovative research in stem cells and biomaterials development have opened new frontiers. Stringent properties like biocompatibility, ability to foster cells, biodegradability and mechanical compliance have been the norm for material selection. Fabrication techniques implemented individually or in conjunction have been used to fabricate scaffolds that best mimic the anisotropic nature of the cardiac extracellular matrix (ECM). Such biomimetic scaffolds provide topographical ...