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Tissue Engineering Using Ceramics and Polymers, 2nd Edition by P.X. Ma, Aldo R Boccaccini

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18

Cartilage tissue engineering

V. Salih,    Plymouth University, UK

Abstract:

The goal of cartilage repair is to induce and provide symptomatic relief and an acceptable joint function to the patient. Recent strategies and those introduced two decades ago have partly achieved this goal. There still remains limited success of long-term regeneration of newly formed tissue. Often, the neocartilage formed in these repair systems is biochemically and mechanically inferior, and very immature. These issues are exacerbated by the anisotropic nature of articular cartilage and also because of its intimate association with the subchondral bone. This failure to develop a mature cartilage combined with a distinct lack of lateral integration between host ...

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