Ultrasound Elastography for Biomedical Applications and Medicine

Ultrasound Elastography for Biomedical Applications and Medicine

by Ivan Z. Nenadic, Matthew W. Urban, James F. Greenleaf, Jean-Luc Gennisson, Miguel Bernal, Mickael Tanter
Released January 2019
Publisher(s): Wiley
ISBN: 9781119021513

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Book description

Ultrasound Elastography for Biomedical Applications and Medicine

Ivan Z. Nenadic, Matthew W. Urban, James F. Greenleaf, Mayo Clinic Ultrasound Research Laboratory, Mayo Clinic College of Medicine, USA

Jean-Luc Gennisson, Miguel Bernal, Mickael Tanter, Institut Langevin – Ondes et Images, ESPCI ParisTech CNRS, France

Covers all major developments and techniques of Ultrasound Elastography and biomedical applications

The field of ultrasound elastography has developed various techniques with the potential to diagnose and track the progression of diseases such as breast and thyroid cancer, liver and kidney fibrosis, congestive heart failure, and atherosclerosis. Having emerged in the last decade, ultrasound elastography is a medical imaging modality that can noninvasively measure and map the elastic and viscous properties of soft tissues.

Ultrasound Elastography for Biomedical Applications and Medicine covers the basic physics of ultrasound wave propagation and the interaction of ultrasound with various media. The book introduces tissue elastography, covers the history of the field, details the various methods that have been developed by research groups across the world, and describes its novel applications, particularly in shear wave elastography.

Key features:

  • Covers all major developments and techniques of ultrasound elastography and biomedical applications.
  • Contributions from the pioneers of the field secure the most complete coverage of ultrasound elastography available.

The book is essential reading for researchers and engineers working in ultrasound and elastography, as well as biomedical engineering students and those working in the field of biomechanics.

Table of contents

  1. Cover
  2. List of Contributors
  3. Section I: Introduction
    1. 1 Editors' Introduction
      1. References
  4. Section II: Fundamentals of Ultrasound Elastography
    1. 2 Theory of Ultrasound Physics and Imaging
      1. 2.1 Introduction
      2. 2.2 Modeling the Response of the Source to Stimuli [ ]
      3. 2.3 Modeling the Fields from Sources [ ]
      4. 2.4 Modeling an Ultrasonic Scattered Field [ ]
      5. 2.5 Modeling the Bulk Properties of the Medium [ ]
      6. 2.6 Processing Approaches Derived from the Physics of Ultrasound [Ω]
      7. 2.7 Conclusions
      8. References
    2. 3 Elastography and the Continuum of Tissue Response
      1. 3.1 Introduction
      2. 3.2 Some Classical Solutions
      3. 3.3 The Continuum Approach
      4. 3.4 Conclusion
      5. Acknowledgments
      6. References
    3. 4 Ultrasonic Methods for Assessment of Tissue Motion in Elastography
      1. 4.1 Introduction
      2. 4.2 Basic Concepts and their Relevance in Tissue Motion Tracking
      3. 4.3 Tracking Tissue Motion through Frequency‐domain Methods
      4. 4.4 Maximum Likelihood (ML) Time‐domain Correlation‐based Methods
      5. 4.5 Tracking Tissue Motion through Combining Time‐domain and Frequency‐domain Information
      6. 4.6 Time‐domain Maximum A Posterior (MAP) Speckle Tracking Methods
      7. 4.7. Optical Flow‐based Tissue Motion Tracking
      8. 4.8 Deformable Mesh‐based Motion‐tracking Methods
      9. 4.9 Future Outlook
      10. 4.10 Conclusions
      11. Acknowledgments
      12. Acronyms
      13. Additional Nomenclature of Definitions and Acronyms
      14. References
  5. Section III: Theory of Mechanical Properties of Tissue
    1. 5 Continuum Mechanics Tensor Calculus and Solutions to Wave Equations
      1. 5.1 Introduction
      2. 5.2 Mathematical Basis and Notation
      3. 5.3 Solutions to Wave Equations
      4. References
    2. 6 Transverse Wave Propagation in Anisotropic Media
      1. 6.1 Introduction
      2. 6.2 Theoretical Considerations from General to Transverse Isotropic Models for Soft Tissues
      3. 6.3 Experimental Assessment of Anisotropic Ratio by Shear Wave Elastography
      4. 6.4 Conclusion
      5. References
    3. 7 Transverse Wave Propagation in Bounded Media
      1. 7.1 Introduction
      2. 7.2 Transverse Wave Propagation in Isotropic Elastic Plates
      3. 7.3 Plate in Vacuum: Lamb Waves
      4. 7.4 Viscoelastic Plate in Liquid: Leaky Lamb Waves
      5. 7.5 Isotropic Plate Embedded Between Two Semi‐infinite Elastic Solids
      6. 7.6 Transverse Wave Propagation in Anisotropic Viscoelastic Plates Surrounded by Non‐viscous Fluid
      7. 7.7 Conclusions
      8. Acknowledgments
      9. References
    4. 8 Rheological Model‐based Methods for Estimating Tissue Viscoelasticity
      1. 8.1 Introduction
      2. 8.2 Shear Modulus and Rheological Models
      3. 8.3 Applications of Rheological Models
      4. References
    5. 9 Wave Propagation in Viscoelastic Materials
      1. 9.1 Introduction
      2. 9.2 Estimating the Complex Shear Modulus from Propagating Waves
      3. 9.3 Wave Generation and Propagation
      4. 9.4 Rheological Models
      5. 9.5 Experimental Results and Applications
      6. 9.6 Summary
      7. References
  6. Section IV: Static and Low Frequency Elastography
    1. 10 Validation of Quantitative Linear and Nonlinear Compression Elastography
      1. 10.1 Introduction
      2. 10.2 Methods
      3. 10.3 Results
      4. 10.4 Discussion
      5. 10.5 Conclusions
      6. Acknowledgement
      7. References
    2. 11 Cardiac Strain and Strain Rate Imaging
      1. 11.1 Introduction
      2. 11.2 Strain Definitions in Cardiology
      3. 11.3 Methodologies Towards Cardiac Strain (Rate) Estimation
      4. 11.4 Experimental Validation of the Proposed Methodologies
      5. 11.5 Clinical Applications
      6. 11.6 Future Developments
      7. References
    3. 12 Vascular and Intravascular Elastography
      1. 12.1 Introduction
      2. 12.2 General Principles
      3. 12.3 Conclusion
      4. References
    4. 13 Viscoelastic Creep Imaging
      1. 13.1 Introduction
      2. 13.2 Overview of Governing Principles
      3. 13.3 Imaging Techniques
      4. 13.4 Conclusion
      5. References
    5. 14 Intrinsic Cardiovascular Wave and Strain Imaging
      1. 14.1 Introduction
      2. 14.2 Cardiac Imaging
      3. 14.3 Vascular Imaging
      4. Acknowledgements
      5. References
  7. Section V: Harmonic Elastography Methods
    1. 15 Dynamic Elasticity Imaging
      1. 15.1 Vibration Amplitude Sonoelastography: Early Results
      2. 15.2 Sonoelastic Theory
      3. 15.3 Vibration Phase Gradient Sonoelastography
      4. 15.4 Crawling Waves
      5. 15.5 Clinical Results
      6. 15.6 Conclusion
      7. Acknowledgments
      8. References
    2. 16 Harmonic Shear Wave Elastography
      1. 16.1 Introduction
      2. 16.2 Basic Principles
      3. 16.3 Ex Vivo Validation
      4. 16.4 In Vivo Application
      5. 16.5 Summary
      6. Acknowledgments
      7. References
    3. 17 Vibro‐acoustography and its Medical Applications
      1. 17.1 Introduction
      2. 17.2 Background
      3. 17.3 Application of Vibro‐acoustography for Detection of Calcifications
      4. 17.4 In Vivo Breast Vibro‐acoustography
      5. 17.5 In Vivo Thyroid Vibro‐acoustography
      6. 17.6 Limitations and Further Future Plans
      7. Acknowledgments
      8. References
    4. 18 Harmonic Motion Imaging
      1. 18.1 Introduction
      2. 18.2 Background
      3. 18.3 Methods
      4. 18.4 Preclinical Studies
      5. 18.5 Future Prospects
      6. Acknowledgements
      7. References
    5. 19 Shear Wave Dispersion Ultrasound Vibrometry
      1. 19.1 Introduction
      2. 19.2 Principles of Shear Wave Dispersion Ultrasound Vibrometry (SDUV)
      3. 19.3 Clinical Applications
      4. 19.4 Summary
      5. References
  8. Section VI: Transient Elastography Methods
    1. 20 Transient Elastography: From Research to Noninvasive Assessment of Liver Fibrosis Using Fibroscan®
      1. 20.1 Introduction
      2. 20.2 Principles of Transient Elastography
      3. 20.3 Fibroscan
      4. 20.4 Application of Vibration‐controlled Transient Elastography to Liver Diseases
      5. 20.5 Other Applications of Transient Elastography
      6. 20.6 Conclusion
      7. References
    2. 21 From Time Reversal to Natural Shear Wave Imaging
      1. 21.1 Introduction: Time Reversal Shear Wave in Soft Solids
      2. 21.2 Shear Wave Elastography using Correlation: Principle and Simulation Results
      3. 21.3 Experimental Validation in Controlled Media
      4. 21.4 Natural Shear Wave Elastography: First In Vivo Results in the Liver, the Thyroid, and the Brain
      5. 21.5 Conclusion
      6. References
    3. 22 Acoustic Radiation Force Impulse Ultrasound
      1. 22.1 Introduction
      2. 22.2 Impulsive Acoustic Radiation Force
      3. 22.3 Monitoring ARFI‐induced Tissue Motion
      4. 22.4 ARFI Data Acquisition
      5. 22.5 ARFI Image Formation
      6. 22.6 Real‐time ARFI Imaging
      7. 22.7 Quantitative ARFI Imaging
      8. 22.8 ARFI Imaging in Clinical Applications
      9. 22.9 Commercial Implementation
      10. 22.10 Related Technologies
      11. 22.11 Conclusions
      12. References
    4. 23 Supersonic Shear Imaging
      1. 23.1 Introduction
      2. 23.2 Radiation Force Excitation
      3. 23.3 Ultrafast Imaging
      4. 23.4 Shear Wave Speed Mapping
      5. 23.5 Conclusion
      6. References
    5. 24 Single Tracking Location Shear Wave Elastography
      1. 24.1 Introduction
      2. 24.2 SMURF
      3. 24.3 STL‐SWEI
      4. 24.4 Noise in SWE/Speckle Bias
      5. 24.5 Estimation of viscoelastic parameters (STL‐VE)
      6. 24.6 Conclusion
      7. References
    6. 25 Comb‐push Ultrasound Shear Elastography
      1. 25.1 Introduction
      2. 25.2 Principles of Comb‐push Ultrasound Shear Elastography (CUSE)
      3. 25.3 Clinical Applications of CUSE
      4. 25.4 Summary
      5. References
  9. Section VII: Emerging Research Areas in Ultrasound Elastography
    1. 26 Anisotropic Shear Wave Elastography
      1. 26.1 Introduction
      2. 26.2 Shear Wave Propagation in Anisotropic Media
      3. 26.3 Anisotropic Shear Wave Elastography Applications
      4. 26.4 Conclusion
      5. References
    2. 27 Application of Guided Waves for Quantifying Elasticity and Viscoelasticity of Boundary Sensitive Organs
      1. 27.1 Introduction
      2. 27.2 Myocardium
      3. 27.3 Arteries
      4. 27.4 Urinary Bladder
      5. 27.5 Cornea
      6. 27.6 Tendons
      7. 27.7 Conclusions
      8. References
    3. 28 Model‐free Techniques for Estimating Tissue Viscoelasticity
      1. 28.1 Introduction
      2. 28.2 Overview of Governing Principles
      3. 28.3 Imaging Techniques
      4. 28.4 Conclusion
      5. References
    4. 29 Nonlinear Shear Elasticity
      1. 29.1 Introduction
      2. 29.2 Shocked Plane Shear Waves
      3. 29.3 Nonlinear Interaction of Plane Shear Waves
      4. 29.4 Acoustoelasticity Theory
      5. 29.5 Assessment of 4th Order Nonlinear Shear Parameter
      6. 29.6 Conclusion
      7. References
  10. Section VIII: Clinical Elastography Applications
    1. 30 Current and Future Clinical Applications of Elasticity Imaging Techniques
      1. 30.1 Introduction
      2. 30.2 Clinical Implementation and Use of Elastography
      3. 30.3 Clinical Applications
      4. 30.4 Future Work in Clinical Applications of Elastography
      5. 30.5 Conclusions
      6. Acknowledgments
      7. References
    2. 31 Abdominal Applications of Shear Wave Ultrasound Vibrometry and Supersonic Shear Imaging
      1. 31.1 Introduction
      2. 31.2 Liver Application
      3. 31.3 Prostate Application
      4. 31.4 Kidney Application
      5. 31.5 Intestine Application
      6. 31.6 Uterine Cervix Application
      7. 31.7 Spleen Application
      8. 31.8 Pancreas Application
      9. 31.9 Bladder Application
      10. 31.10 Summary
      11. References
    3. 32 Acoustic Radiation Force‐based Ultrasound Elastography for Cardiac Imaging Applications
      1. 32.1 Introduction
      2. 32.2 Acoustic Radiation Force‐based Elastography Techniques
      3. 32.3 ARF‐based Elasticity Assessment of Cardiac Function
      4. 32.4 ARF‐based Image Guidance for Cardiac Radiofrequency Ablation Procedures
      5. 32.5 Conclusions
      6. Funding Acknowledgements
      7. References
    4. 33 Cardiovascular Application of Shear Wave Elastography
      1. 33.1 Introduction
      2. 33.2 Cardiovascular Shear Wave Imaging Techniques
      3. 33.3 Clinical Applications of Cardiovascular Shear Wave Elastography
      4. 33.4 Summary
      5. References
    5. 34 Musculoskeletal Applications of Supersonic Shear Imaging
      1. 34.1 Introduction
      2. 34.2 Muscle Stiffness at Rest and During Passive Stretching
      3. 34.3 Active and Dynamic Muscle Stiffness
      4. 34.4 Tendon Applications
      5. 34.5 Clinical Applications
      6. 34.6 Future Directions
      7. References
    6. 35 Breast Shear Wave Elastography
      1. 35.1 Introduction
      2. 35.2 Background
      3. 35.3 Breast Elastography Techniques
      4. 35.4 Application of CUSE for Breast Cancer Detection
      5. 35.5 CUSE on a Clinical Ultrasound Scanner
      6. 35.6 Limitations of Breast Shear Wave Elastography
      7. 35.7 Conclusion
      8. Acknowledgments
      9. References
    7. 36 Thyroid Shear Wave Elastography
      1. 36.1 Introduction
      2. 36.2 Background
      3. 36.3 Role of Ultrasound and its Limitation in Thyroid Cancer Detection
      4. 36.4 Fine Needle Aspiration Biopsy (FNAB)
      5. 36.5 The Role of Elasticity Imaging
      6. 36.6 Application of CUSE on Thyroid
      7. 36.7 CUSE on Clinical Ultrasound Scanner
      8. 36.8 Conclusion
      9. Acknowledgments
      10. References
  11. Section IX: Perspective on Ultrasound Elastography
    1. 37 Historical Growth of Ultrasound Elastography and Directions for the Future
      1. 37.1 Introduction
      2. 37.2 Elastography Publication Analysis
      3. 37.3 Future Investigations of Acoustic Radiation Force for Elastography
      4. 37.4 Conclusions
      5. Acknowledgments
      6. References
  12. Index
  13. End User License Agreement

Product information

  • Title: Ultrasound Elastography for Biomedical Applications and Medicine
  • Author(s): Ivan Z. Nenadic, Matthew W. Urban, James F. Greenleaf, Jean-Luc Gennisson, Miguel Bernal, Mickael Tanter
  • Release date: January 2019
  • Publisher(s): Wiley
  • ISBN: 9781119021513