Right now is probably the best time in history to start your own company. Here's what you need to know about the startup landscape. Read Chapter 1 of The Hardware Startup.
Brady Forrest runs Highway1, PCH's accelerator. He cofounded and shepherds Ignite, a global talk series. He's a Venture Advisor to 500 Startups and helps arts organizations via CAST-sf.org. Formerly, he worked on a number of things at O'Reilly Media, including the Radar blog, Web 2.0 Expo, Where 2.0, ETech, and Foo Camp. Most years, you can find him on the playa.
At some point, all successful hardware startups will face the challenge of manufacturing their products at scale.