3.4. Limitations

Despite the recent progress in development of new bioink materials for 3D bioprinting, there are still several challenges in this emerging field. Further advancements are essential in bioink technology including synthesis and processing of new materials for bioprinting. The main objectives are to minimize cell loss and maximize cell–cell interactions, vascularize large-scale tissue constructs, improve mechanical properties, and gain a comprehensive understanding of additional compounds for supporting 3D bioprinted constructs. Although a large number of hydrogels offer great potential for tissue engineering, a limited number has been adopted in bioprinting due to their lack of bioprintability.
Hydrogels are the most favorable material ...

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