Advanced Organic Chemistry

4

Elimination Reactions

LEARNING OBJECTIVES

By the end of this chapter you should be familiar with

• Elimination reactions and what factors favour elimination over substitution.
• The three important mechanisms of elimination reactions and orientation of the double bond formed.
• The importance of conformation in elimination reactions and the role of the leaving group.
• Stereochemistry of elimination reactions and pyrolytic eliminations.

4.1 INTRODUCTION

Reactions in which a molecule of two atoms or groups is removed from a compound and which are not replaced by other atoms or groups are referred to as elimination. It belongs to one of the important class of organic reactions. The atoms or groups can be bound to carbon atoms and/or to heteroatoms ...