Advanced Thermoforming, 2nd Edition

Chapter 37Blister Packaging of Syringes

For the packaging of pharmaceutical applications, hygiene is of utmost importance. Thus the control of the packaging process is critical. In this chapter an application for the fully automatic packaging of ready‐filled syringes is detailed. For this application a multilayer film consisting of A‐PET/PE is used. The sealing film is made of PA/PE. The loaded and closed blister tray is loaded into a carton box in an end‐of‐line packaging machine. From a downstream equipment the filled syringe, two cannulas, and an instruction label are fed to the thermoforming/cartoning machine. Easy opening of the packaging, namely peeling of the sealing film, as well as completeness of the packaging contents are essential criteria. For the pharmaceutical sector product tracing must be possible. For this reason the production line must be validated and have the possibility to create batch protocols.

For applications that fulfill these demands, the packaging machines of, for example, Schubert GmbH could be utilized. Standard components are used that are assembled based on the conception of the line. These machines function according to the top‐loading principle (TLM). From a standard range of components, two‐axis, three‐axis, or four‐axis robots can be chosen. The TLM packaging line consists of two main parts: a thermoforming, loading, and closing machine and a downstream end‐of‐the‐line packaging machine. The scope of supply also comprises a manufacturing ...