February 2015
Intermediate to advanced
276 pages
7h 8m
English
Blagoj Ristevski1 Faculty of Information and Communication Technologies—Bitola, St. Kliment Ohridski University, Bitola, Macedonia1 Corresponding author: email address: blagoj.ristevski@uklo.edu.mk
This chapter describes biological backgrounds of regulatory relationships in living cells, high-throughput experimental technologies, and application of computational approaches in reverse engineering of microRNA (miRNA)-mediated and gene regulatory networks (GRNs). The most commonly used models for GRNs inference based on Boolean networks, Bayesian networks, dynamic Bayesian networks, association networks, novel two-stage ...