Anion-Binding Catalysis

71,2,3‐Triazoles and 1,2,3‐Triazolium Ions as Catalysts

Kohsuke Ohmatsu and Takashi Ooi

Nagoya University, Institute of Transformative Bio‐Molecules, Graduate School of Engineering, Department of Molecular and Macromolecular Chemistry, D2‐1 Furo‐cho, Chikusa, Nagoya, 464‐8601, Japan

7.1 Introduction

1,2,3‐Triazole is a unique heterocycle with phenomenal stability compared to other organic compounds having contiguous three nitrogen atoms. The history of triazole synthesis can be traced back to late nineteenth century when 1,3‐dipolar cycloaddition between phenyl azide and dimethyl acetylenedicarboxylate was reported [1]. While this synthetic method attracted less attention for a long period, the concept of click chemistry, introduced by Sharpless ...