8

Real-World Applications of Bayesian Networks

We will now apply the concepts we introduced in the previous chapters to the analysis of two real-world data sets from the life sciences: a protein-signalling data set from which we want to discover the interactions and the pathways characterising some biological processes in human cells, and a medical diagnostic data set which we will use as a basis to predict a human's body composition.

8.1 Learning Protein-Signalling Networks

BNs provide a versatile tool for the analysis of many kinds of biological data such as single-nucleotide polymorphism (SNP) data and gene expression profiles. Following the work of Friedman et al. (2000), the expression level or the allele frequency of each gene is ...

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