Bioinformatics Tools for Pharmaceutical Drug Product Development

1Introduction to Bioinformatics, AI, and ML for Pharmaceuticals

Vivek P. Chavda¹*, Disha Vihol², Aayushi Patel³, Elrashdy M. Redwan^4,5 and Vladimir N. Uversky^6†

¹Department of Pharmaceutics and Pharmaceutical Technology, L. M. College of Pharmacy, Ahmedabad, Gujarat, India

²Department of Phytopharmacy and Phytomedicine, School of Pharmacy, Gujarat Technological University, Ahmedabad, Gujarat, India

³Pharmacy Section, L. M. College of Pharmacy, Ahmedabad, Gujarat, India

⁴Department of Biological Sciences, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia

⁵Therapeutic and Protective Proteins Laboratory, Protein Research Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications, New Borg EL-Arab, Alexandria, Egypt

⁶Department of Molecular Medicine and Byrd Alzheimer’s Research Institute, Morsani College of Medicine, University of South Florida, Tampa, FL, USA

Abstract

Bioinformatics is a growing field that has emerged in recent years. The use of computational applications for protein sequence analysis in the early 1960s created the groundwork for bioinformatics. Alongside, developments in molecular biology techs evolved DNA analysis, leading to simpler manipulation of DNA, its sequencing, and computer science, suggesting the development of compatible and more powerful computers with innovative software for performing bioinformatics tasks. Biological Big Data collection when analyzed with ...