February 2014
Intermediate to advanced
344 pages
11h 24m
English
Content preview from Biomedical Imaging
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Brain imaging: assessing therapy responses using quantitative imaging biomarkers
M. Hwang, M. Oborski, C. Laymon, F. Imani and J. Mountz, University of Pittsburgh, USA
Abstract:
Neuroimaging is essential for both the diagnosis and evaluation of the therapeutic response of intracranial tumors. Measurement of structural changes in tumor morphology after institution of therapy using magnetic resonance imaging (MRI) serves as the current gold standard for monitoring therapeutic response; however, information of prognostic value cannot be obtained until weeks after the initiation of treatment. Positron emission tomography (PET) using radiolabled ligands that trace physiologic processes offers promise as a method for early therapy response assessment, ...