Imaging methods for detection of joint degeneration
T. Thote, S. Moran, A. Lin, N.J. Willett and R.E. Guldberg, Georgia Institute of Technology, USA
C.P. Neu, Purdue University, USA
Abstract:
Osteoarthritis (OA) is the most common form of joint disease, affecting over 33% of people over 65 years old. The patho-physiology of OA is complex and manifested by changes at the molecular, cellular, and tissue levels. High resolution, three-dimensional (3D) imaging methods provide the opportunity to quantitatively assess changes in the morphology and composition of multiple articular joint tissues in small animal models. Two of the main imaging modalities used in research to examine articular tissue changes are magnetic resonance imaging MRI and ...
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