14In Vivo Applications for Nanomaterials in Biosensors

Abhinay Thakur1 and Ashish Kumar2*

1 Department of Chemistry, Lovely Professional University, Phagwara, Punjab, India

2 NCE, Bihar Engineering University, Department of Science and Technology, Government of Bihar, Bihar, India

Abstract

Owing to the inherent link between human health and medical science, the rapid detection and monitoring of several lethal heavy metals, malignant cells, etc., requires more consideration. Currently, the integration of nanotechnology (such as functionalized nanoparticles (NPs), nanowires, nanotubes and nanofibers) with biosensors has greatly evolved from the in vitro studies offering rapid, simple, selective and sensitive detection methods for the analysis of heavy metals, toxins, and malignant cells. Nanomaterials (NMs) can enhance the surface of the sensors, transducing regions, increasing catalytic behaviors with the emergence of numerous innovative signal transduction technologies in biosensors. They offer a high surface-to-volume proportion, as well as a controlled geometry and architecture that encourages miniaturization, which is a useful feature when specimen volume is an issue. This chapter explores present and prospective breakthroughs in nanotechnology-based biosensors for real time assessment of targeted several analytes and toxicity mechanisms in living creatures, using primary data sets from 2018 onwards. Innovative biosensing technologies centered on unique sensing components ...

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