August 2009
Intermediate to advanced
648 pages
17h 35m
English
Consider the data from Koch and Edwards (1988) displayed in Table 4.1. The information comes from a randomized, double-blind clinical trial investigating a new treatment for rheumatoid arthritis. Investigators compared the new treatment with a placebo; the response measured was whether there was no, some, or marked improvement in the symptoms of rheumatoid arthritis.
| Improvement | |||||
|---|---|---|---|---|---|
| Gender | Treatment | None | Some | Marked | Total |
| Female | Test Drug | 6 | 5 | 16 | 27 |
| Female | Placebo | 19 | 7 | 6 | 32 |
| Total | 25 | 12 | 22 | 59 | |
| Male | Test Drug | 7 | 2 | 5 | 14 |
| Male | Placebo | 10 | 0 | 1 | 11 |
| Total | 17 | 2 | 6 | 25 | |
These data comprise a set of two 2 × 3 tables. There is interest in the association between treatment and degree of improvement, adjusting for gender effects. Degree of ...
Read now
Unlock full access