Computational Biophysics of the Skin

Computational Biophysics of the Skin

by Bernard Querleux
Released July 2014
Publisher(s): CRC Press
ISBN: 9789814463850

Read it now on the O’Reilly learning platform with a 10-day free trial.

O’Reilly members get unlimited access to books, live events, courses curated by job role, and more from O’Reilly and nearly 200 top publishers.

Start your free trial

Book description

The accessibility of the skin in vivo has resulted in the development of non-invasive methods in the past 40 years that offer accurate measurements of skin properties and structures from microscopic to macroscopic levels. However, the mechanisms involved in these properties are still only partly understood. Similar to many other domains, including biomedical engineering, numerical modeling has appeared as a complementary key actor for improving our knowledge of skin physiology.

This book presents, for the first time, the contributions that focus on scientific computing and numerical modeling to offer a deeper understanding of the mechanisms involved in skin physiology. The book is structured around some skin properties and functions, including optical and biomechanical properties and skin barrier function and homeostasis, with—for each of them—several chapters that describe either biological or physical models at different scales.

Table of contents

  1. Cover (1/2)
  2. Cover (2/2)
  3. Contents (1/3)
  4. Contents (2/3)
  5. Contents (3/3)
  6. Foreword
  7. Preface
  8. Part 1: Skin Color
  9. Chapter 1: Multilayer Modeling of Skin Color and Translucency (1/5)
  10. Chapter 1: Multilayer Modeling of Skin Color and Translucency (2/5)
  11. Chapter 1: Multilayer Modeling of Skin Color and Translucency (3/5)
  12. Chapter 1: Multilayer Modeling of Skin Color and Translucency (4/5)
  13. Chapter 1: Multilayer Modeling of Skin Color and Translucency (5/5)
  14. Chapter 2: Dermal Component–Based Optical Modeling of Skin Translucency: Impact on Skin Color (1/8)
  15. Chapter 2: Dermal Component–Based Optical Modeling of Skin Translucency: Impact on Skin Color (2/8)
  16. Chapter 2: Dermal Component–Based Optical Modeling of Skin Translucency: Impact on Skin Color (3/8)
  17. Chapter 2: Dermal Component–Based Optical Modeling of Skin Translucency: Impact on Skin Color (4/8)
  18. Chapter 2: Dermal Component–Based Optical Modeling of Skin Translucency: Impact on Skin Color (5/8)
  19. Chapter 2: Dermal Component–Based Optical Modeling of Skin Translucency: Impact on Skin Color (6/8)
  20. Chapter 2: Dermal Component–Based Optical Modeling of Skin Translucency: Impact on Skin Color (7/8)
  21. Chapter 2: Dermal Component–Based Optical Modeling of Skin Translucency: Impact on Skin Color (8/8)
  22. Chapter 3: Mathematics and Biological Process of Skin Pigmentation (1/6)
  23. Chapter 3: Mathematics and Biological Process of Skin Pigmentation (2/6)
  24. Chapter 3: Mathematics and Biological Process of Skin Pigmentation (3/6)
  25. Chapter 3: Mathematics and Biological Process of Skin Pigmentation (4/6)
  26. Chapter 3: Mathematics and Biological Process of Skin Pigmentation (5/6)
  27. Chapter 3: Mathematics and Biological Process of Skin Pigmentation (6/6)
  28. Part 2: Skin Biomechanics
  29. Chapter 4: State-of-the-Art Constitutive Models of Skin Biomechanics (1/8)
  30. Chapter 4: State-of-the-Art Constitutive Models of Skin Biomechanics (2/8)
  31. Chapter 4: State-of-the-Art Constitutive Models of Skin Biomechanics (3/8)
  32. Chapter 4: State-of-the-Art Constitutive Models of Skin Biomechanics (4/8)
  33. Chapter 4: State-of-the-Art Constitutive Models of Skin Biomechanics (5/8)
  34. Chapter 4: State-of-the-Art Constitutive Models of Skin Biomechanics (6/8)
  35. Chapter 4: State-of-the-Art Constitutive Models of Skin Biomechanics (7/8)
  36. Chapter 4: State-of-the-Art Constitutive Models of Skin Biomechanics (8/8)
  37. Chapter 5: Fiber-Matrix Models of the Dermis (1/6)
  38. Chapter 5: Fiber-Matrix Models of the Dermis (2/6)
  39. Chapter 5: Fiber-Matrix Models of the Dermis (3/6)
  40. Chapter 5: Fiber-Matrix Models of the Dermis (4/6)
  41. Chapter 5: Fiber-Matrix Models of the Dermis (5/6)
  42. Chapter 5: Fiber-Matrix Models of the Dermis (6/6)
  43. Chapter 6: Cellular-Scale Mechanical Model of the Human Stratum Corneum (1/5)
  44. Chapter 6: Cellular-Scale Mechanical Model of the Human Stratum Corneum (2/5)
  45. Chapter 6: Cellular-Scale Mechanical Model of the Human Stratum Corneum (3/5)
  46. Chapter 6: Cellular-Scale Mechanical Model of the Human Stratum Corneum (4/5)
  47. Chapter 6: Cellular-Scale Mechanical Model of the Human Stratum Corneum (5/5)
  48. Part 3: Skin Barrier
  49. Chapter 7: Mathematical Models of Skin Permeability: Microscopic Transport Models and Their Predictions (1/6)
  50. Chapter 7: Mathematical Models of Skin Permeability: Microscopic Transport Models and Their Predictions (2/6)
  51. Chapter 7: Mathematical Models of Skin Permeability: Microscopic Transport Models and Their Predictions (3/6)
  52. Chapter 7: Mathematical Models of Skin Permeability: Microscopic Transport Models and Their Predictions (4/6)
  53. Chapter 7: Mathematical Models of Skin Permeability: Microscopic Transport Models and Their Predictions (5/6)
  54. Chapter 7: Mathematical Models of Skin Permeability: Microscopic Transport Models and Their Predictions (6/6)
  55. Chapter 8: Cellular Scale Modelling of the Skin Barrier (1/6)
  56. Chapter 8: Cellular Scale Modelling of the Skin Barrier (2/6)
  57. Chapter 8: Cellular Scale Modelling of the Skin Barrier (3/6)
  58. Chapter 8: Cellular Scale Modelling of the Skin Barrier (4/6)
  59. Chapter 8: Cellular Scale Modelling of the Skin Barrier (5/6)
  60. Chapter 8: Cellular Scale Modelling of the Skin Barrier (6/6)
  61. Chapter 9: Molecular Scale Modeling of Human Skin Permeation (1/10)
  62. Chapter 9: Molecular Scale Modeling of Human Skin Permeation (2/10)
  63. Chapter 9: Molecular Scale Modeling of Human Skin Permeation (3/10)
  64. Chapter 9: Molecular Scale Modeling of Human Skin Permeation (4/10)
  65. Chapter 9: Molecular Scale Modeling of Human Skin Permeation (5/10)
  66. Chapter 9: Molecular Scale Modeling of Human Skin Permeation (6/10)
  67. Chapter 9: Molecular Scale Modeling of Human Skin Permeation (7/10)
  68. Chapter 9: Molecular Scale Modeling of Human Skin Permeation (8/10)
  69. Chapter 9: Molecular Scale Modeling of Human Skin Permeation (9/10)
  70. Chapter 9: Molecular Scale Modeling of Human Skin Permeation (10/10)
  71. Chapter 10: Accessing the Molecular Organization of the Stratum Corneum Using High-Resolution Electron Microscopy and Computer Simulation (1/9)
  72. Chapter 10: Accessing the Molecular Organization of the Stratum Corneum Using High-Resolution Electron Microscopy and Computer Simulation (2/9)
  73. Chapter 10: Accessing the Molecular Organization of the Stratum Corneum Using High-Resolution Electron Microscopy and Computer Simulation (3/9)
  74. Chapter 10: Accessing the Molecular Organization of the Stratum Corneum Using High-Resolution Electron Microscopy and Computer Simulation (4/9)
  75. Chapter 10: Accessing the Molecular Organization of the Stratum Corneum Using High-Resolution Electron Microscopy and Computer Simulation (5/9)
  76. Chapter 10: Accessing the Molecular Organization of the Stratum Corneum Using High-Resolution Electron Microscopy and Computer Simulation (6/9)
  77. Chapter 10: Accessing the Molecular Organization of the Stratum Corneum Using High-Resolution Electron Microscopy and Computer Simulation (7/9)
  78. Chapter 10: Accessing the Molecular Organization of the Stratum Corneum Using High-Resolution Electron Microscopy and Computer Simulation (8/9)
  79. Chapter 10: Accessing the Molecular Organization of the Stratum Corneum Using High-Resolution Electron Microscopy and Computer Simulation (9/9)
  80. Part 4: Skin Fluids and Components
  81. Chapter 11: Water Diffusion through Stratum Corneum (1/4)
  82. Chapter 11: Water Diffusion through Stratum Corneum (2/4)
  83. Chapter 11: Water Diffusion through Stratum Corneum (3/4)
  84. Chapter 11: Water Diffusion through Stratum Corneum (4/4)
  85. Chapter 12: Accurate Multiscale Skin Model Suitable for Determining the Sensitivity and Specificity of Changes of Skin Components (1/9)
  86. Chapter 12: Accurate Multiscale Skin Model Suitable for Determining the Sensitivity and Specificity of Changes of Skin Components (2/9)
  87. Chapter 12: Accurate Multiscale Skin Model Suitable for Determining the Sensitivity and Specificity of Changes of Skin Components (3/9)
  88. Chapter 12: Accurate Multiscale Skin Model Suitable for Determining the Sensitivity and Specificity of Changes of Skin Components (4/9)
  89. Chapter 12: Accurate Multiscale Skin Model Suitable for Determining the Sensitivity and Specificity of Changes of Skin Components (5/9)
  90. Chapter 12: Accurate Multiscale Skin Model Suitable for Determining the Sensitivity and Specificity of Changes of Skin Components (6/9)
  91. Chapter 12: Accurate Multiscale Skin Model Suitable for Determining the Sensitivity and Specificity of Changes of Skin Components (7/9)
  92. Chapter 12: Accurate Multiscale Skin Model Suitable for Determining the Sensitivity and Specificity of Changes of Skin Components (8/9)
  93. Chapter 12: Accurate Multiscale Skin Model Suitable for Determining the Sensitivity and Specificity of Changes of Skin Components (9/9)
  94. Chapter 13: Model-Based Quantification of Skin Microcirculatory Perfusion (1/5)
  95. Chapter 13: Model-Based Quantification of Skin Microcirculatory Perfusion (2/5)
  96. Chapter 13: Model-Based Quantification of Skin Microcirculatory Perfusion (3/5)
  97. Chapter 13: Model-Based Quantification of Skin Microcirculatory Perfusion (4/5)
  98. Chapter 13: Model-Based Quantification of Skin Microcirculatory Perfusion (5/5)
  99. Part 5: Skin Homeostasis
  100. Chapter 14: Graphical Multi-Scale Modeling of Epidermal Homeostasis with EPISIM (1/8)
  101. Chapter 14: Graphical Multi-Scale Modeling of Epidermal Homeostasis with EPISIM (2/8)
  102. Chapter 14: Graphical Multi-Scale Modeling of Epidermal Homeostasis with EPISIM (3/8)
  103. Chapter 14: Graphical Multi-Scale Modeling of Epidermal Homeostasis with EPISIM (4/8)
  104. Chapter 14: Graphical Multi-Scale Modeling of Epidermal Homeostasis with EPISIM (5/8)
  105. Chapter 14: Graphical Multi-Scale Modeling of Epidermal Homeostasis with EPISIM (6/8)
  106. Chapter 14: Graphical Multi-Scale Modeling of Epidermal Homeostasis with EPISIM (7/8)
  107. Chapter 14: Graphical Multi-Scale Modeling of Epidermal Homeostasis with EPISIM (8/8)
  108. Chapter 15: Heuristic Modelling Applied to Epidermal Homeostasis (1/13)
  109. Chapter 15: Heuristic Modelling Applied to Epidermal Homeostasis (2/13)
  110. Chapter 15: Heuristic Modelling Applied to Epidermal Homeostasis (3/13)
  111. Chapter 15: Heuristic Modelling Applied to Epidermal Homeostasis (4/13)
  112. Chapter 15: Heuristic Modelling Applied to Epidermal Homeostasis (5/13)
  113. Chapter 15: Heuristic Modelling Applied to Epidermal Homeostasis (6/13)
  114. Chapter 15: Heuristic Modelling Applied to Epidermal Homeostasis (7/13)
  115. Chapter 15: Heuristic Modelling Applied to Epidermal Homeostasis (8/13)
  116. Chapter 15: Heuristic Modelling Applied to Epidermal Homeostasis (9/13)
  117. Chapter 15: Heuristic Modelling Applied to Epidermal Homeostasis (10/13)
  118. Chapter 15: Heuristic Modelling Applied to Epidermal Homeostasis (11/13)
  119. Chapter 15: Heuristic Modelling Applied to Epidermal Homeostasis (12/13)
  120. Chapter 15: Heuristic Modelling Applied to Epidermal Homeostasis (13/13)
  121. Back Cover

Product information

  • Title: Computational Biophysics of the Skin
  • Author(s): Bernard Querleux
  • Release date: July 2014
  • Publisher(s): CRC Press
  • ISBN: 9789814463850