Neo-Urinary Conduit™
Abstract
The Neo-Urinary Conduit™ is a tubular neo-organ composed of native-like urinary tissue mediating efflux of urine from the body in patients requiring urinary diversion. Its development from concept to clinical trials is presented here as an illustrative example highlighting issues common to bioprocess development of novel TE/RM products based on cell/biomaterial composite constructs.
Keywords
scaffold
smooth muscle cell
regeneration
tissue engineering
urinary conduit
urinary diversion
biomaterial
neo-organ
5.1 Introduction
During efforts to transition the Neo-Bladder Replacement™ (Chapter 4) through the clinical trials process, alternative strategies for mediating efflux of urine from the body were considered. ...
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