Tendon tissue regeneration
L.A. Bosworth, The University of Manchester, UK
Abstract:
Tendons are highly fibrous tissues that are capable of withstanding particularly high tensile loads. Unfortunately, tendons can degenerate as a consequence of repetitive loading, which may lead to their eventual rupture. Current clinical interventions commonly result in a healed tendon that is both biochemically and biomechanically inferior and highly susceptible to re-rupture. An unmet clinical need remains and many researchers are seeking to address this with the use of degradable biomaterials to create tissue engineered tendons. This chapter focuses on how the electrospinning technique can create scaffolds which closely resemble the natural tendon ...
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