Cell culture systems for stem cell research
K. Meade, R.J Holley and C.L.R Merry, The University of Manchester, UK
Abstract:
Embryonic stem (Es) cells have the capacity to form any cell type in the adult organism. However, their propagation and differentiation is limited by current two dimensional (2d) culture techniques which offer little flexibility in terms of surface structure and functionalisation with bioactive molecules. Electrospinning is one of the few fabrication methods that can create a dry non-woven mesh that recreates the fibrous architecture of the extracellular matrix (ECM). Despite the versatility of this well established technique, few studies have investigated the potential of electrospun meshes either to maintain ...
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