Chapter 6Design of Artificial Supramolecular Protein Assemblies by Enzymatic Bioconjugation for Biocatalytic Reactions

Geisa A.L.G. Budinova, Yutaro Mori and Noriho Kamiya

Concise Definition of Subject

Self-assembly processes in biological systems generate well-organized, higher-order protein structures with unique functions. Protein cross-linking can occur by covalent or non-covalent linkage of proteins that have natural affinity in vivo, generating intrinsic architectures, such as viral particles, cell-surface pilus nanoarchitectures, and biomass degrading nanomachines (e.g., cellulosome). To mimic this singular natural biomolecular assembly system, the design of artificial conjugates is becoming very attractive. Several strategies have ...

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