Emerging Areas in Bioengineering

Chapter 26Advanced Genetic Engineering of Microbial Cells for Biosensing Applications

Do Hyun Kim, Byung Jo Yu and Moon Il Kim

26.1 Introduction

Biosensors, which are comprised of both biological and transducing elements to produce readily detectable signal, have gathered a significant growing interest as one of the most convenient methods to allow rapid detection of target analytes in the field. They generally exhibit high specificity, sensitivity, portability, and capacity for real-time inspection and monitoring and thus have been widely applied in biotechnology and related fields [1, 2]. As biological sensing elements, diverse biomolecules such as enzymes, antibodies, receptors, nucleic acids, or cells have been used to provide specific ...