Chapter 34Controlled Delivery Systems of Protein and Peptide Therapeutics
Hwiwon Lee, Minsoo Cho, Jeong Ho Lee, Jong Hwan Mun, Byung Woo Hwang, Hyemin Kim and Sei Kwang Hahn
34.1 Introduction
Protein and peptide therapeutics have been widely investigated as effective therapeutic agents for the treatment of various diseases, including cancer, metabolic, and autoimmune disorders [1]. Their global market is dramatically growing with more than hundreds of approved biopharmaceuticals [1]. Protein and peptide therapeutics have several advantages such as higher affinity and specificity to target molecules with low toxicity than small-molecule chemical drugs [2]. However, the administered protein and peptide therapeutics are unstable and easily degraded ...
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