Chapter 40Recent Advances in Mass Spectrometry-Based Proteomic Methods for Discovery of Protein Biomarkers for Complex Human Diseases
Sangchul Rho*, Hyobin Jeong*, Sehyun Chae*, Hee-Jung Jung, Sanghyun Ahn, Yun-Hwa Kim, Ju-Young Lee, Soyoung Choi and Daehee Hwang
* These authors equally contributed to this work.
Concise Definition of Subject
Biomarkers refer to “characteristics objectively measured and evaluated as indicators of pathological processes or pharmacologic responses to therapeutic treatments.” DNAs, mRNAs, proteins, and metabolites have been measured from various tissues and body fluid samples (e.g., blood, urine, and ascites) collected from patients with diseases. Of these types of biomarkers, protein biomarkers have been extensively ...
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