O'Reilly logo

Emerging Nanotechnologies for Diagnostics, Drug Delivery and Medical Devices by Abhirup Mandal, Kishore Cholkar, Ashim K Mitra

Stay ahead with the world's most comprehensive technology and business learning platform.

With Safari, you learn the way you learn best. Get unlimited access to videos, live online training, learning paths, books, tutorials, and more.

Start Free Trial

No credit card required

Chapter 4

Diagnosis and Drug Delivery to the Brain

Novel Strategies

Abhirup Mandal1, Rohit Bisht2, Dhananjay Pal1, and Ashim K. Mitra1     1University of Missouri–Kansas City, Kansas City, MO, United States     2University of Auckland, Auckland, New Zealand

Abstract

For decades, tremendous efforts have been made by biomedical and pharmaceutical researchers to treat diseases affecting the central nervous system (CNS). The blood–brain barrier effectively protects the brain, but poses a formidable challenge to drug delivery. Many conventional drugs cannot cross the BBB in therapeutic concentrations (less than 1%). As a result proper treatments of various CNS diseases such as Alzheimer, brain tumors, and human immunodeficiency virus infection are compromised. ...

With Safari, you learn the way you learn best. Get unlimited access to videos, live online training, learning paths, books, interactive tutorials, and more.

Start Free Trial

No credit card required