Emerging Nanotechnologies in Dentistry

Chapter 12. Nano-Apatitic Composite Scaffolds for Stem Cell Delivery and Bone Tissue Engineering

H.H.K. Xu¹²³, M.D. Weir¹, L. Zhao¹, J.L. Moreau¹, D.D. Arola¹³ and C.G. Simon⁴

¹Department of Endodontics, Prosthodontics and Operative Dentistry, University of Maryland Dental School, Baltimore, MD, USA

²Center for Stem Cell Biology and Regenerative Medicine, University of Maryland School of Medicine, Baltimore, MD, USA

³Department of Mechanical Engineering, University of Maryland, Baltimore County, MD, USA

⁴Polymers Division, National Institute of Standards and Technology Gaithersburg, MD, USA

Contents

12.1 Introduction 189

12.2 Development of Nano-Apatitic and Macroporous Scaffolds 190

12.3 Cell Infiltration into Scaffold 192

12.4 Biomimetic Nano-Apatite–Collagen ...