Chapter 4

Hierarchical k-Means

A Hybrid Clustering Algorithm and Its Application to Study Gene Expression in Lung Adenocarcinoma

Mohammad Shabbir Hasan; Zhong-Hui Duan    Department of Computer Science, College of Arts and Sciences, University of Akron, Akron, USA


DNA microarray technology is a very useful tool to get information for various biological processes by providing a convenient way to investigate expression levels of thousands of genes in a collection of related samples. Moreover, as a discovery tool, DNA microarrays have the potential to enhance the understanding of the molecular basis of different diseases by simultaneously providing information on thousands of genes. Researchers using DNA microarray technology often ...

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