Chapter 24

SMIR

A Web Server to Predict Residues Involved in the Protein Folding Core

Ruben Acuña1; Zoé Lacroix1; Jacques Chomilier2,3; Nikolaos Papandreou4    1 Scientific Data Management Laboratory, Arizona State University, Tempe, AZ, USA2 IMPMC, Sorbonne Universités, Université Pierre et Marie Curie, CNRS, MNHN, IRD, Paris, France3 RPBS, Université Paris Diderot, Paris, France4 Department of Biotechnology, Agricultural University of Athens, Athens, Greece

Abstract

Motivation: Protein folding is the critical spontaneous phase when the protein gains its structural conformation, and hence, its functional shape. Should any error in the process affect its folding, the protein structure may fail to fold properly and perform its function. In ...

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