12

METALS IN BIOLOGICAL SYSTEM

Metal ions play essential roles in biological systems

12.1 INTRODUCTION

Metal ions have been associated with biological systems for billions of years. The metals are important ingredients in life because some are present in enzymes, in structural features like the Ca in bones, in transport systems like Fe in haemoglobin, in control systems like Na and K in nervous system, etc. For instance, the divalent Mg and Ca ions play important regulatory roles in cells. The divalent metals like Ca2+ and Mg2+ prevent cytotoxicity and in vivo antagonize Cd-induced carcinogenesis. Hence, metal ions play crucial roles in life processes, and they are also used as inorganic drugs for curing many diseases because of their biocompatibility. ...

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