20. Epigenetics and technology—hairpin-based antisensing
RNA interference, known as RNAi, is a fascinating phenomenon that enables us to understand how organisms control expression of endogenous and exogenous RNAs. Moreover, RNAi represents a powerful research and therapeutic tool for the regulation of gene expression in cells. The use of RNAi in functional genomics makes it possible to analyze the function of a specific gene. Its use in agriculture represents the knockdown of specific genes and the pathways for either removing an undesirable trait or adding a new, desirable one. The landmark discovery of the hairpin RNAi construct as an efficient sequence-dependent trigger of gene silencing provided a foundation for a new RNAi technology. This ...
Get Epigenetics in Health and Disease now with the O’Reilly learning platform.
O’Reilly members experience books, live events, courses curated by job role, and more from O’Reilly and nearly 200 top publishers.
