Essentials of Molecular Biology

2

Gene Organization

CONCEPT OUTLINE

• Introduction
  • Genes
  • Non-coding DNA
  • Repetitive DNA sequences
  • Satellite DNAs
  • Cot value – Renaturation kinetics of DNA
  • Chromatin
  • Chromosomes
  • Prokaryotic gene organization
  • Gene organization in eukaryotes

INTRODUCTION

The hereditary nature of every living organism is defined by its ‘genome’. The genome consists of a long sequence of nucleic acid that provides the information needed to construct an organism. A genome consists of the entire set of chromosomes for any particular organism. It, therefore, comprises a series of DNA molecules (one for each chromosome), each of which contains many genes. The genome itself does not perform any function, rather a sequence of nucleic acids determines the hereditary ...