Chapter 7: Linkage and Crossing Over - Genetics and Genomics [Book]

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Meiotic chromosomes in diakinesis of grasshopper showing chiasmata, the site of crossing over.

7

LINKAGE AND CROSSING OVER

CONCEPT OUTLINE

Linkage and Recombination

■ Examples from pea and Drosophila

■ Coupling and repulsion hypothesis

Detection of Linkage

■ Linkage groups

Crossing Over and Recombination

■ Mechanism of crossing over

■ Cytological basis of crossing over

■ Linkage maps

Chromosome Mapping in Drosophila

■ Single crossovers

■ Multiple exchanges

■ Three-point mapping in Drosophila

■ interference and coincidence

Mapping and Linkage Map in Maize

Tetrad analysis and linkage map in Neurospora

Mapping Human Chromosome

■ Pedigree ...

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