Genetics and Genomics

Bacteriophage T4 infecting a bacteria.

(SOURCE: SHUTTERSTOCK).

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NUCLEIC ACIDS AND CHROMATIN

CONCEPT OUTLINE

Search for Genetic Material

■ Bacterial transformation

■ Bacteriophage infection

■ Additional evidences

■ Tobacco mosaic virus infection

Chemistry of Nucleic Acids

■ Building blocks

■ Base composition studies

■ X-ray diffraction studies

Watson and Crick DNA model

■ Spatial structure of DNA

■ Forces stabilizing DNA structure

Structural Variants of Nucleic Acids

■ Comparison of DNA and RNA

■ Variants of RNAs

■ Variants of DNA

Analytical Techniques to Investigate DNA and RNA

■ Denaturation and renaturation

■ Molecular hybridization

■ Reassociation ...