book

Implantable Sensor Systems for Medical Applications

by A Inmann, D Hodgins

January 2013

Intermediate to advanced

544 pages

16h 50m

English

Woodhead Publishing

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Title page
Table of Contents
Copyright
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Woodhead Publishing Series in Biomaterials
Foreword
Introduction
Part I: Fundamentals of implantable systems
Chapter 1: Materials for implantable systems
Abstract:1.1 Introduction1.2 Interactions between materials and the biological medium1.3 Electrodes1.4 Preferred electrode metals, compounds and polymers1.5 Leads and interconnects1.6 Packaging1.7 Surface preparation1.8 Conclusions1.9 Future trends1.10 Sources of further information1.11 Acknowledgements

Chapter 2: Material–tissue interfaces in implantable systems
Abstract:2.1 Introduction2.2 Fundamental requirements of material–tissue interfaces2.3 Material selection for implantable systems2.4 Design considerations and packaging concepts2.5 Approaches to reduce reactions at the material–tissue interface2.6 Conclusions2.7 Future trends2.8 Sources of further information
Chapter 3: Packaging and coating materials for implantable devices
Abstract:3.1 Introduction3.1.1 Background76 Implantable sensor systems for medical applications 3.1.3 Current packaging and coating strategies3.2 Packaging of the passive device surface80 Implantable sensor systems for medical applications 3.2.2 Silicone3.3 Coating of active device surfaces3.4 Coatings and barriers for drug release3.5 Enhancement of surface biocompatibility3.6 Conclusions3.7 Future trends
Chapter 4: Microassembly and micropackaging of implantable systems
Abstract:4.1 Introduction4.2 Components of an implanted sensor system4.3 Microassembly4.4 Micropackaging4.5 Conclusions4.6 Future trends4.7 Sources of further information
Chapter 5: Electrode array design and fabrication for implantable systems
Abstract:5.1 Introduction5.2 General requirements for implantable electrode arrays5.3 Materials for implantable electrodes5.4 The processing of silicone as a substrate material5.5 Coating layers for microelectrodes5.6 Fabrication of electrodes using platinum5.7 Microelectrode arrays – design and fabrication5.8 Advantages and disadvantages of existing fabrication processes5.9 Risks5.10 Conclusions5.11 Future trends5.12 Sources of further information
Chapter 6: Biofuel cells as sustainable power sources for implantable systems
Abstract:6.1 Introduction6.2 Implantable biofuel cells6.3 Design considerations6.4 State-of-the-art and practical examples6.5 Conclusions and future trends6.6 Sources of further information
Part II: Challenges of implantable systems
Chapter 7: Biocompatibility of implantable systems
Abstract:7.1 Introduction7.2 The nature of the biological milieu7.3 The course of events following insertion of an implantable system7.4 Interfacial interactions7.5 Biological and chemical processes which can affect implantable systems7.6 Modelling protein adsorption7.7 The immune response7.8 Hydrodynamic aspects of biocompatibility7.9 Tribological aspects of biocompatibility7.10 Corrosion7.11 Cell–implant interactions7.12 The metrology and evaluation of biocompatibility7.13 Conclusions7.14 Future trends7.15 Sources of further information
Chapter 8: Sterilisation considerations for implantable sensor systems
Abstract:8.1 Introduction8.2 Global markets and the regulatory context8.3 Methods for sterilisation of medical devices8.4 Sterilisation of implantable sensor systems8.5 Conclusions8.6 Future trends8.7 Sources of further information
Chapter 9: Protection of data confidentiality and patient privacy in medical sensor networks
Abstract:9.1 Introduction9.2 Challenges9.3 Review of existing methods and their limitations9.4 Secure authentication of medical sensing information9.5 Performance evaluation of the Securing User Access to Medical Sensing Information (SecMed) method9.6 Discussion9.7 Conclusions9.8 Future trends9.9 Sources of further information
Chapter 10: Developing active implantable medical devices in a regulated environment
Abstract:10.1 Introduction10.2 The route to market10.3 The medical device
Part III: Applications of implantable systems
Chapter 11: Microelectromechanical systems (MEMS) for in vivo applications
Abstract:11.1 Introduction to MEMS11.2 Requirements for in vivo MEMS11.3 In vivo physiological MEMS sensors11.4 In vivo MEMS actuators11.5 Biocompatibility11.6 Conclusions11.7 Future trends11.8 Sources of further information
Chapter 12: Tripolar interfaces for neural recording
Abstract:12.1 Introduction12.2 The signal12.3 Noise12.4 Common-mode interference effects12.5 Interference by external potential gradients12.6 Models and illustrations12.7 Future trends12.8 Conclusions12.9 Acknowledgements12.11 Appendix: list of symbols
Chapter 13: Sensors for motor neuroprostheses
Abstract:13.1 Introduction13.2 Unique requirements of motor neuroprostheses13.3 Clinical significance of motor neuroprostheses13.4 Motor neuroprosthesis sensors13.5 Motor neuroprosthesis control algorithms and sensor signal processing13.6 Motor neuroprosthesis implantable sensor applications13.7 Network topology design of sensor systems for use in motor neuroprostheses13.8 Conclusions13.9 Future trends13.10 Sources of further information
Chapter 14: Implantable wireless body area networks
Abstract:14.1 Introduction to Implanted Body Area Networks (IBANs)14.2 Applications of IBANs14.3 Wireless communication into and out of the body14.4 Healthy Aims demonstration of IBANs14.5 Conclusions14.6 Future trends14.7 Sources of further information
Chapter 15: Retina implants
Abstract:15.1 Introduction15.2 Background15.3 The eye and the retina15.4 Overview and approaches to retina implants15.5 Technical implementation15.6 Clinical trials15.7 Conclusions15.8 Future trends15.9 Sources of further information
Index

Content preview from Implantable Sensor Systems for Medical Applications

Biocompatibility of implantable systems

J.J. Ramsden, Collegium Basilea (Institute of Advanced Study) Switzerland

Abstract:

The essence of biocompatibility is the ability to interact with proteins without denaturing them. The issue is, therefore, a question of interfacial interactions. In some cases, a simple mean-field approach based on mesoscale surface tension determinations can be a guide. However, the recently gained understanding that the stability of the majority of known proteins is ruled by the degree of desolvation of structure-determining backbone hydrogen bonds, implies that microscopic considerations of local interfacial interactions are required to predict the behaviour of proteins brought into contact with an artificial ...

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Implantable Sensor Systems for Medical Applications

by A Inmann, D Hodgins

Biocompatibility of implantable systems

Abstract:

Become an O’Reilly member and get unlimited access to this title plus top books and audiobooks from O’Reilly and nearly 200 top publishers, thousands of courses curated by job role, 150+ live events each month,
and much more.