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Introduction to Mathematical Oncology by Steffen E. Eikenberry, John D. Nagy, Yang Kuang

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Chapter 1

Introduction to Theory in Medicine

1.1 Introduction

On September 5, 1976, a man named MabaloLokela was admitted to the Yambuku Mission Hospital in what is now the Democratic Republic of the Congo [8, Ch. 5]. Gravely ill, Lokela was suffering an intense fever, headache, chest pain and nausea. He vomited blood and had bloody diarrhea. Medical personnel recognized the signs of a hemorrhagic fever, but they were still largely in the dark. A variety of pathogens cause hemorrhagic fever, and there was no time to determine which one was causing this particular case. Lokela was clearly in serious trouble. Unfortunately, his health care workers failed to recognize that they were also in serious trouble.

Roughly speaking, Lokela’s tissues, including ...

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