September 2018
Intermediate to advanced
1178 pages
48h 30m
English
Content preview from Labs on Chip
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Electrophoresis separation systems are based either on the effect of an electrical field or on the combined effect of the electrical field and of the hydrodynamic velocity distribution to divide different species in a sample, so as to purify the target species for an assay.
The simpler way of performing such an operation is to transport gel electrophoresis from its base macroscopic arrangement (see Section 3.6) to a microscopic on-chip design [119,120]. This is in principle not difficult if a suitable electrophoresis chamber is prepared in the chip and gel is injected into it during the back-end chip fabrication stage. An example of such an arrangement is shown in Figure 8.83. Here, a sample is injected into a ...