Medicinal Chemistry, 2nd Edition

Chapter 1

Drug Discovery and Development

LEARNING OBJECTIVES

• Understand what is medicinal chemistry

• List of several stages of drug development

• Cost and duration of a drug to be brought from the bench to the market

• Identification of a key drug target

• Identification of lead chemical and how it can be developed as a drug

• Ethical issues in testing drugs on human beings

• Understand related terminologies like IND, NCE, NDA, and MAA

• Stages of different clinical studies

• Explain the different methods of drug discovery research

• Identification of drug-like compounds from nature

• Understand the importance of history behind drug discovery and how it can be further explored

• Explain the process of metabolism of drug in the biological system and its importance ...